What do Singapore, London, Tokyo, and Chicago have in common? They are all centers of arts and culture, and are top performers in business activity, human capital, information exchange, and political engagement. Furthermore, they also exhibit great potential for amplified global engagement in the future. As cities across the world increasingly compete for capital, people, and ideas, what are the key drivers of success? And as Chicago’s role as a global city continues to evolve, how can the city maintain its cultural and competitive edge and maximize the benefits of global integration while minimizing risks?